The Western Maryland Regional Crime Laboratory has been accredited since November 2010. The WMRCL is currently accredited through the American National Standards Institute National Accreditation Board (ANAB) under the international test requirements set forth in ISO 17025 and ANAB supplemental requirements. Laboratory accreditation is a continuing process that involves a number of audits that review and evaluate management practices, personnel qualifications, technical procedures, the quality assurance programs, and facilities. Forensic laboratory accreditation is voluntary, but is required to receive some federal funding.

The Maryland Department of Health (MDH) requires all forensic laboratories within the state to be licensed, regardless of accreditation status, through the Forensic Laboratories division. This licensing is a continual process and involves an annual audit similar to that of ANAB.